Frequently Asked Questions
PBC is a chronic autoimmune liver disease that slowly destroys the bile ducts in the liver.
Symptoms include fatigue, itching, dry eyes, jaundice, and abdominal discomfort.
Diagnosis involves blood tests for antimitochondrial antibodies (AMA), liver function tests, and imaging.
The exact cause is unknown, but it involves autoimmune damage to bile ducts.
Treatment includes ursodeoxycholic acid (UDCA) and newer drugs like obeticholic acid to slow progression.
There is no cure, but treatment can slow disease progression and manage symptoms.
Maintaining a healthy diet, avoiding alcohol, and managing symptoms like itching improve quality of life.
Yes, over time PBC can cause liver scarring leading to cirrhosis and liver failure.
Complications include osteoporosis, fat-soluble vitamin deficiencies, and portal hypertension.
Liver tests should be done every 3-6 months to monitor disease activity.
Liver transplant may be needed in advanced cases with liver failure.
Pregnancy is possible but requires close monitoring due to potential liver function changes.
UDCA helps improve bile flow and reduces liver inflammation.
Report worsening fatigue, jaundice, abdominal swelling, or severe itching.
PBC is not directly inherited but may have a genetic predisposition.